The DynaPro Plate Reader offers dynamic light scattering (DLS) and static light scattering (SLS) measurements of the size, molecular weight, concentration and interactions of proteins, nanoparticles and other macromolecules in situ in industry-standard microwell plates.

The DynaPro Plate Reader is operated by DYNAMICS, our powerful software package for collecting, analyzing, and reporting automated batch dynamic and static light scattering data.ĭYNAMICS is offered with a 21 CFR Part 11 compliant Security Pack option, enabling the use of the DynaPro Plate Reader in a GMP environment. Its automation is particularly valued to screen fractions during process development and then to quantify CQAs in quality control. Even viscosity of concentrated protein solutions can be screened across dozens of formulations in a single plate.įor nanoparticle formulation and process development, including viral vectors, non-viral vectors and nano-drug delivery vehicles, the DynaPro adds particle concentration / physical titer to basic DLS measurements of size and polydispersity. Measure aggregation, aggregate size distributions, changes in solution molecular weight, and propensity for aggregation: indicators of both thermal stability (T onset, T m, T agg) and colloidal stability (A 2/B 22, k D) may be quantified with plate-based DLS and SLS. Even if you need to run just a handful of samples, it's a great productivity booster.įor biotherapeutic development, the DynaPro Plate Reader is a comprehensive solution for stability evaluation. The DynaPro excels at high-throughput sizing and screening of pharmaceutical and nanoparticle formulations to enable novel workflows that simply would not be possible with other DLS instruments. Revolutionize your performance by replacing your conventional, cuvette-based dynamic light scattering unit with the automated DynaPro ® Plate Reader III.

High-throughput, automated, dynamic and static light scattering Upgrade to plates Dynamic & Electrophoretic Light Scattering.

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